30+ simulations · non-toxic · immune-compatible

The future of cancer therapy is computed.

VisionSearch Bio builds simulation-first medicine. MilanoQ, our lead platform, targets resistant cancers with safe natural compounds — validated in silico before a single dose.

Explore MilanoQ → Read the white paper
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IC50 (µM) — tumor apoptosis
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CD8+ immune reactivation
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Long-term non-relapse rate
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Chronic-use safety validated
The problem

Resistant cancers outrun today's medicine.

Poor durability

Mutation-driven cancers like KRAS/NRAS Q61H relapse frequently, even after aggressive first-line therapy.

Severe toxicity

FOLFOX and FOLFIRI suppress the immune system and cause serious organ stress.

Escape & recurrence

Conventional chemotherapy fails to prevent long-term resistance and disease recurrence.

MilanoQ compound docking with immune activation
A safe natural compound docking a mutated target — while CD8+ T-cells reactivate around it.
The MilanoQ platform

Efficacy of chemotherapy. Without the toxicity.

MilanoQ is a next-generation, immune-compatible, mutation-targeted therapeutic system — built entirely from safe, natural compounds and designed to work with the body, not against it.

01 / TARGET

Mutation-specific

Designed to engage resistant driver mutations such as NRAS/KRAS Q61H directly.

02 / INDUCE

Tumor apoptosis

Drives programmed tumor-cell death at an IC50 of ~11.5 µM in modeling.

03 / REACTIVATE

Immune re-engagement

Restores CD8+ T-cell activity (~4.1×) — normally the domain of biologics.

04 / PROTECT

Relapse suppression

Suppresses mutation escape (<4%) for durable, long-term control.

Validated performance

Deeply modeled. Rigorously measured.

One of the most deeply modeled non-toxic oncology platforms in development — validated across quantum pharmacology, immune mapping, and whole-body microdosing.

Efficacy signals

Simulation-validated outcomes across key oncology endpoints
Tumor apoptosis (IC50 potency)~11.5 µM
CD8+ immune reactivation~4.1×
Long-term non-relapse rate~72%
Mutation-escape suppression<4%
Oral bioavailability (enteric-coated)~87%
Values are computationally validated in silico. Wet-lab and preclinical confirmation are the next milestones.

Validation coverage

Breadth of the in-silico validation stack
Technology stack

An unprecedented in-silico validation engine.

Quantum binding simulations

Molecular binding modeled with Qiskit + PennyLane for precision before synthesis.

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MOISL engine

Tumor–immune ecosystem modeling of how the therapy reshapes the microenvironment.

TEHM

T-cell exhaustion horizon modeling to predict durability of immune response.

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WB-MEM

Whole-body microdosing map projecting distribution and exposure across tissues.

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Virtual clinical trial

1,000-avatar simulated cohort to stress-test response and variability.

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3D tumor organoids

Organoid modeling plus enteric-coated delivery simulation (~87% bioavailability).

Pipeline

One platform. Many resistant tumors.

MilanoQ has demonstrated performance and/or is actively being evaluated across a broad set of hard-to-treat indications.

Colorectal cancerKRAS / NRAS Q61H — lead indication
Lead / modeled
Lung adenocarcinomaKRAS+
Evaluation
Multiple myelomaHematologic
Evaluation
Glioblastoma · DIPGCNS / pediatric brain tumor
Exploratory
Pancreatic · MelanomaSolid tumors
Exploratory
TNBC · NSCLCBreast / lung
Exploratory
Progress reflects depth of in-silico validation to date
Why this matters

The strengths of three modalities — in one.

AttributeChemotherapyCheckpoint / biologicsMilanoQ
Tumor-killing efficacyHighVariableChemo-comparable
Systemic toxicitySevereModerateNon-toxic (natural)
Immune activationSuppressesStrong~4.1× CD8+
Resistant-mutation reachLimitedLimitedMulti-tumor
Combination-readyLimitedYesDCV / checkpoint combo
Next steps

Entering partner conversations and seed-stage investment.

CRO-led preclinical validation, dendritic-cell-vaccine integration, and IND-enabling studies. The full technical case is in the white paper.

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MilanoQ Investor White PaperPDF · Simulation-validated therapeutic platform
Download
Get in touch

Let's talk about what comes next.

Whether you're an investor, a CRO, or a strategic partner — we'd love to share the deeper data and discuss collaboration.

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